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Clindamycin contraindications

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  • Patients also should be tested for a G6PD deficiency before starting chloroquine or hydroxychloroquine. Clindamycin belongs to the family of medicines called antibiotics. It is well concentrated in bone and excreted in bile and urine. 1 List of Excipients. Jan 15, 2023 · Azithromycin is an antimicrobial medication used to treat and manage bacterial infections, including community-acquired pneumonia and sexually transmitted diseases. Aug 8, 2023 · Contraindications. Stock Availability. Therefore, the administration of Clindamycin Hydrochloride Capsules should be avoided in those species sensitive to the gastrointestinal effects of clindamycin (see CONTRAINDICATIONS). Classification: It belongs to the group of lincosamides. Assess for diarrhea and possible colitis. com. The dose is usually 8 to 16 milligrams Common Uses. difficile -associated diarrhea may be higher with clindamycin compared with some other antibiotics. pinpoint red spots on the skin. Medical Information e-mail. Clindamycin Phosphate Topical Solution USP, 1% is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis. This activity reviews the indications, contraindications clindamycin topical + methotrexate if oral methotrexate use, consider alternative or monitor CBC, renal fxn: combo may incr. 4. following infusion to prevent hypotension. Either a previous hypersensitivity to any 4-aminoquinoline compounds or the underlying presence of retinopathy is the only absolute exclusions to these medications. With systemic use: Clindamycin is active against Gram-positive cocci, including streptococci and penicillin-resistant staphylococci, and also against many anaerobes, especially Bacteroides fragilis. Clindamycin 300mg PO BID x 7 days; PID. Clindamycin is used to treat bacterial infections. Common Uses. com. (See "Clostridioides difficile infection Feb 8, 2023 · Clindamycin phosphate has a molecular weight of 504. Hypersensitivity to clindamycin, lincomycin, or any component of the formulation. Contraindications: History of hypersensitivity to lincomycin and clindamycin. Aug 11, 2021 · Hemodialysis and peritoneal dialysis are not effective in removing clindamycin from the serum. rapid weight gain. Fever, chills, or sore throat; any unexplained bruising or bleeding; or feeling very tired or weak. 3 Contraindications. PO (Mild-mod) 450mg PO q6h x 14 days; Use with ceftriaxone or cefoxitin/probenecid if no proceeding IV treatment; IV (Severe) 900mg IV q8; Use with gentamicin and switch to PO after 24h of clinical improvement; Babesiosis. Feb 17, 2024 · Cephalosporins are β-lactam antimicrobials used to manage various infections caused by both gram-positive and gram-negative bacteria. You could have more side effects. Lotion 1%: 60 mL. May 28, 2018 · Give parenteral dosage for hospitalized clients only. 97 and its chemical name is Methyl 7-chloro-6,7,8-trideoxy-6- (1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside 2- (dihydrogen phosphate). inflammatory bowel dz. Lung abscess. Childn regardless of body wt Severe infection Min recommended dose: 300 mg (base) daily. 5. Jun 1, 2024 · For oral dosage forms (capsules and solution): For treatment of bacterial infections: Adults—150 to 300 milligrams (mg) every 6 hours. Topical applications: Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin. Clindamycin is an antibiotic that is usually reserved for treating anaerobic infections or other serious infections caused by gram-positive bacteria in penicillin-allergic people. It is used to treat intestinal amebiases, liver amebiasis, bacterial septicemia, bone and joint infections, meningitis, brain abscess, endocarditis, endometritis, bacterial Clindamycin is a lincosamide antibiotic that has been approved by the US Food and Drug Administration for the treatment of anaerobic, streptococcal, and staphylococcal infections. pv@bbukltd. Contraindications . 4 CONTRAINDICATIONS . It is cytotoxic to facultative anaerobic microorganisms. Clindamycin phosphate gel is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis. If your or your child's symptoms do not improve, or if they Clindamycin is widely distributed in the body, including into bone, but does not distribute into cerebrospinal fluid. Contraindications. Vaginal gel: 2% clindamycin (present as clindamycin phosphate) as a clear, colorless, viscous gel in a 25 g tube. Clindamycin is a broad-spectrum antibiotic used to treat susceptible infections of the skin, bone and wounds. nausea or vomiting. Keep container tightly closed. Cefiderocol is a novel siderophore cephalosporin that exhibits remarkable antibacterial activity. Childn Serious infection 15 mg/kg/day. Vaginal itching or discharge. Clindamycin belongs to a class of antibiotics called lincosamides. Cleocin and generic: Insert 1 applicatorful (100 mg of clindamycin) into the vagina once a day, preferably at bedtime, for 3 or 7 days. The risk of C. Clindamycin protein binding is concentration-dependent and ranges from 60-94%. CONTRAINDICATIONS . Cleocin (Clindamycin) can also be used for other purposes not listed in this medication guide. It is important that your doctor check your or your child's progress after treatment. Clindesse is an intravaginal cream containing clindamycin phosphate 2%. Cleocin is an antibiotic used to treat various infections caused by gram-positive and anaerobic bacteria. 4 Special Warnings and Precautions for Use. Prevention of Prosthetic Joint Infection. methotrexate active metabolite levels, efficacy (decreased absorption; intestinal metab. Clindamycin Injection, USP in vials contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. Bacterial Endocarditis Prevention. Assess extent of infections and if improvement occurs. 1% benzoyl peroxide. Jan 5, 2022 · For patients with these underlying cardiac conditions, prophylaxis is recommended for all dental procedures that involve manipulation of gingival tissue or the periapical region of teeth or perforation of the oral mucosa. Feb 28, 2024 · Contraindications. Clindamycin hydrochloride: Capsules 75mg, 150mg, 300mg Clindamycin palmitate hydrochloride: Granules for oral solution 75mg/5ml Clindamycin phosphate injectable infusion in D5W 300mg/50ml, 600mg/50ml, 900mg/50ml Injection: 150mg base/ml, 300mg base/2ml, 600mg base/4ml, 900mg base/6ml. Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. (2) Topical gel: 1. +44 (0)203 384 7188. 4. 1. CLEOCIN HCl is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. Sep 14, 2023 · Developmental toxicity studies performed in rats and mice using oral doses of clindamycin up to 600 mg per kg per day (240 and 120 times the amount of clindamycin in the highest recommended adult human dose based on mg per m 2, respectively) or subcutaneous doses of clindamycin up to 250 mg per kg per day (100 and 50 times the amount of CNS toxoplasmosis: clindamycin 600 mg IV q6h or clindamycin 450 mg-600 mg PO q6h + pyrimethamine 200 mg PO loading dose, then 50-7 5mg PO q24hd + leucovorin 10-20 mg q24h. 5 mg 3 times daily. Hemodialysis and peritoneal dialysis are not effective in removing clindamycin from the serum. Thus, clindamycin should be avoided for 3 days before and after oral typhoid vaccination. Hypersensitivity Descriptions. Clindamycin can be used for infections due to clindamycin - and erythromycin -susceptible strains. Special warnings and precautions for use Severe hypersensitivity reactions, including severe skin reactions such as drug reaction with Dec 23, 2022 · Cleocin (Clindamycin) is used to treat serious infections caused by bacteria. It has several contraindications, such as live bacterial vaccines, microbiota oral, and neuromuscular blockers. Clindamycin Phosphate Topical Solution USP, 1% is available as follows: 30 mL applicator bottle (NDC 45802-562-01) 60 mL applicator bottle (NDC 45802-562-02) STORAGE. Clindamycin, a lincosamide antibiotic active against gram positive bacteria and anaerobic organisms, has long been known to alter the intestinal microbiome and increase the risk of Clostridium difficile infections. Clindamycin 150 mg Capsules, Hard - Summary of Product Characteristics (SmPC) by Brown & Burk UK Ltd. Clindamycin is also indicated in the treatment of CONTRAINDICATIONS. For more severe infections, 300 to 450 mg every 6 hours. clindamycin- and erythromycin-susceptible strains. Vitamin K antagonists: Jul 31, 2021 · Learn about use of medicines, side effects and proper storage. Vaccines: Oral typhoid vaccine is inactivated by concomitant administration of antibacterials. It is commonly used to treat infections involving the skin and soft tissues, bone and joints. rash with flat lesions or small raised lesions on the skin. There are 86 drugs known to interact with clindamycin, along with 4 disease interactions. pain during sexual intercourse. clindamycin. Dosage and Administration Dosing: Adult. Jul 10, 2023 · Clotrimazole is a synthetic imidazole with a broad spectrum of antimycotic activity. hypersensitivity to drug or ingredient. Penicillins. Clindamycin is used to treat serious bacterial infections, including some infections that are resistant to other antibiotics. Give daily dosage in 3 or 4 equally divided doses. Clindamycin Phosphate Topical Solution is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis. Jan 11, 2023 · Clindamycin is a lincosamide antibiotic that has been approved by the US Food and Drug Administration for the treatment of anaerobic, streptococcal, and staphylococcal infections. Adult Serious infection 150 mg every 6 hr. It works by slowing or stopping the growth of bacteria. This is to make sure that the infection is cleared up completely, and to allow your doctor to check for any unwanted effects. Administer IV over 20-60 minutes. Nursing considerations Assessment . Clotrimazole is effective in the treatment of skin infections such as athlete's foot, jock itch, ringworm, pityriasis versicolor, intertrigo, and Nov 19, 2023 · Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7 (S)-chloro-substitution of the 7 (R)-hydroxyl group of the parent antibiotic lincomycin. Jun 7, 2024 · Contraindications. A total of 86 drugs are known to interact with clindamycin . V. Clindamycin capsules are contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin, lincomycin or any of the ingredients as listed under Section 6. Clindamycin is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and internal organs. Nov 28, 2023 · The use of Clindamycin Hydrochloride Capsules, USP occasionally results in overgrowth of non-susceptible organisms such as clostridia and yeasts. Take orally with a full glass of water to prevent Jul 26, 2023 · Bottom Line. The gel contains allantoin, carbopol 974P, methylparaben, polyethylene glycol 400, propylene glycol, sodium hydroxide, and purified water. Do not use in horses, rabbits Nov 17, 2023 · CLEOCIN PEDIATRIC (clindamycin palmitate HCl) is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Introduction. The solution contains isopropyl alcohol 50% v/v, propylene glycol, purified water, and sodium hydroxide (to adjust the pH to between 4. Miscellaneous Indications. 07%, partially due to increased occurrence in elderly patients as well as improved diagnostic strategies. Apply a thin layer of CABTREO to the affected areas once daily. This medication is given by injection into a vein or muscle as directed by your doctor, usually 2 to 4 times a day. clindamycin topical + methotrexate if oral methotrexate use, consider alternative or monitor CBC, renal fxn: combo may incr. Hypersensitivity reactions Apr 16, 2024 · Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7 (S)-chloro-substitution of the 7 (R)-hydroxyl group of the parent antibiotic lincomycin. 3. Clindamycin Hydrochloride Capsules, USP are contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. DESCRIPTION. Rash, sometimes severe skin reactions. Contraindications / Cautions . Administration instructions: clindamycin capsules should be taken with a full glass of water to avoid esophageal irritation. Abnormal heart rhythm. If you are 60 or older, use this medicine (clindamycin capsules) with care. Oct 23, 2022 · The typical dosing is as follows: Vaginal cream. This activity reviews the indications, action, and contraindications for clindamycin as a valuable agent in managing various infections. It may be used alone or with one or more other medicines that are used on the skin or taken by mouth for acne. If any of these effects last or get worse, tell your doctor or pharmacist promptly. An average peak serum level of 2. Clindesse: Insert 1 prefilled applicator (100 mg of clindamycin) into the vagina once at any time of the day. Usual dose: Aug 5, 2023 · Clindamycin is part of combination therapy for the following: Clindamycin can be used for infections (eg, skin and soft-tissue infections) in communities where community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is common; whether clindamycin is useful depends on local resistance patterns. CLEOCIN T Topical Solution, CLEOCIN T Topical Gel and CLEOCIN T Topical Lotion are contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis. The dosage is based on your medical Feb 28, 2024 · Contraindications. Myasthenia gravis is a rare autoimmune disease with a prevalence of approximately 14 to 20 cases per 100,000 people. Hypersensitivity. Clindamycin can be used for infections (eg, skin and soft-tissue infections) in communities where community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is common; whether clindamycin is useful depends on local resistance patterns. Chloroquine and hydroxychloroquine have few contraindications. 0). Children weighing 10 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. HOW SUPPLIED. Clindamycin is also contraindicated in patients with hypersensitivity to clindamycin, lincomycin, or any of its components. 45 mg benzyl alcohol added as preservative in each mL. 1-3 Overall, the prevalence of myasthenia gravis is increasing in the United States with an annual growth rate of about 1. Dosage/Direction for Use. This drug has Apr 28, 2024 · lower back or side pain. Adult: 600-1,200 mg daily. Clindamycin phosphate topical solution USP, 1% contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per milliliter. difficile infection with resistant strains Jul 30, 2023 · 3. In children weighing ≤10 kg, manufacturer recommends a minimum dosage of 37. We administered 300 mg of clindamycin intravenously at 12-h intervals for 2 days to patients with acute and chronic hepatitis, cirrhosis, and controls to May 7, 2023 · 4. This medicine may cause serious allergic reactions, including anaphylaxis. BenzaClin Topical Gel also contains benzoyl peroxide for topical use. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. 1 Hypersensitivity . Burning, itching, dryness, redness, oily skin or skin peeling may occur. Background. This medicine may be given to patients who have had an allergic reaction to penicillin. Penicillin V and G are prototype beta-lactam antibiotics and function by acting as D-Ala-D-Ala structural analogs, binding penicillin-binding proteins and blocking the transpeptidase cross-linking of peptidoglycan within the bacterial cell walls []. Because of potential adverse gastrointestinal effects, do not administer to rabbits, hamsters, guinea pigs, horses, chinchillas or ruminating animals. Feb 28, 2024 · Contraindications. There are four major categories of penicillin drugs, all of which have the same mechanism of action. Feb 2, 2015 · Main results. Protein binding. epocrates. Jun 1, 2024 · pain in the lower back or side. May 23, 2023 · Clindamycin is also used in the treatment of streptococcal pharyngitis, acne vulgaris, bacterial vaginosis, and severe pelvic inflammatory disease. 50 mcg/mL was reached in 45 minutes; serum levels averaged 1. Mar 1, 2021 · Contraindications for Clindamycin Phosphate Topical Solution. 51 mcg/mL at 3 hours and 0. Severe infection 20 mg/kg in 3-4 divided doses. inhibited, decr. no pulse or blood pressure. Clindamycin. More severe infection 300 mg every 8 hr. Topical clindamycin may also be used for other problems as determined by your doctor. May 8, 2024 · Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. With IV, keep in bed for 30 min. Medical Information Fax. Intramuscular, Intravenous. The 5 generations of cephalosporins demonstrate efficacy in treating skin and soft tissue infections, pneumonia, meningitis, and other infections. Blood tests may be needed to check for unwanted effects. Care is also necessary for antibiotic use as bacterial and fungal superinfections may occur. Click to view Climaxin detailed prescribing information. Monitor liver and renal function. Clindamycin will not work for colds, flu, or other virus infections. Respiratory infections. Hypersensitivity reactions may occur. (2) Not for oral, ophthalmic, or intravaginal use. Clindamycin Hydrochloride Capsules, USP contain clindamycin hydrochloride equivalent to 150 mg or 300 mg of clindamycin. Contraindications for Cleocin. Some Potential Side Effects. It can also be applied on the skin to treat acne. One user-filled single-dose disposable applicator delivers 5 g of gel containing 100 mg of clindamycin. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent compound lincomycin. beans. Vaginal gel. Clindamycin is a semisynthetic antibiotic produced by a 7 (S)-chloro Clindamycin antagonises the effects of the above anticholinesterases. pain in the lower back or side. If you have questions, talk with the doctor. Streptococcal infections and staphylococcal infections. Aug 5, 2023 · Pneumocystis jirovecii pneumonia. 0 - 7. no breathing. Its use to treat certain infections, such as toxoplasmosis, is “off label” or “extra Sep 23, 2010 · Serum level studies with a 150 mg oral dose of clindamycin hydrochloride in 24 normal adult volunteers showed that clindamycin was rapidly absorbed after oral administration. pain, tenderness, or swelling of the foot or leg. Severe skin reactions may happen with this drug. History: Allergy to clindamycin, history of asthma or other allergies, allergy to tartrazine (in 75- and 150-mg capsules); hepatic or renal dysfunction; lactation; history of regional enteritis or ulcerative colitis; history of antibiotic associated colitis Feb 27, 2024 · Contraindications. avoid: latex contraceptive use during tx and x72h after D/C. Jun 1, 2024 · Precautions. Do not administer Clindesse to individuals with a history of hypersensitivity to clindamycin or other May 26, 2022 · Apply a thin film of Clindamycin Phosphate Topical Solution USP, 1% twice daily to affected area. The most commonly reported adverse effect is mild to moderate maculopapular rash, but severe skin reactions, including toxic epidermal necrolysis, have also been reported. 5 mg disodium edetate and 9. The review includes a total of 42 trials, and 40 of these trials contributed data on 4240 participants. Each mL contains the equivalent of 150 mg clindamycin, 0. Adults: 300mg PO q 6 hours; IV: 600mg to 1200mg/day divided q 12 – 6 hours (1200 to 2700mg/day divided for serious infections); topical: apply to affected area q 12 hours; Intra-vaginal cream: One applicatorful hs for 3 or 7 days . Mar 17, 2015 · Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin. conversion to active metabolite) Find patient medical information for Clindamycin Phosphate(Topical) topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. It is in the macrolide class of antimicrobials. This medicine is available only with your doctor's prescription. Pledgets, topical 1%: #60 Solution, topical 1%: (30 mL, 60 mL) Vaginal Suppository: 100 mg #3. 5,6 Inpatient clindamycin use has been linked to a number of nosocomial outbreaks of C. Clindamycin is in the drug class lincomycin derivatives . Babesiosis. Clindamycin is used to treat the following conditions: Aspiration Pneumonia. [1] Clotrimazole is an FDA-approved drug to treat oral candidiasis, vaginal candidiasis, and dermatomycoses. Canadian labeling: Additional contraindications (not in US labeling): Oral clindamycin: Infants <30 days of age. Clindamycin Hydrochloride Capsules, USP contain clindamycin hydrochloride, USP equivalent to 75 mg, 150 mg, or 300 mg of clindamycin. methotrexate levels, risk of serious infection, myelosuppression, nephrotoxicity, other adverse effects; may decr. 7, 6. Its major disadvantage is its propensity to cause antibiotic-associated diarrhea, including Clostridioides difficile colitis. Identified precautions. Of the total drug interactions, 6 are major, 78 are moderate, and 2 are minor. Hepatotoxicity has been noted by several investigators during parenteral use of clindamycin, and some have reported that drug half-life is prolonged in the presence of liver disease. Remember that this medication has been Feb 17, 2020 · Contraindications. How to use Clindamycin Phosphate Vial. Anaerobic infections, Susceptible Gram-positive infections, Susceptible infections. Table. Clindamycin is contraindicated in patients with a history of pseudomembranous colitis and ulcerative colitis. Should May 19, 2023 · Clindamycin hydrochloride is the hydrated hydrochloride salt of clindamycin. Bacteremia. Warnings CONTRAINDICATIONS. Clindamycin hydrochloride capsules, USP contain clindamycin hydrochloride equivalent to 150 mg or 300 mg of clindamycin. Prevention of Infective Endocarditis. Antibiotics such as clindamycin will not work for Descriptions. May 24, 2023 · Contraindications. The disorders treated by azithromycin are important causes of infectious disease morbidity and mortality in the United States. painful or difficult urination. colitis hx, abx-associated. conversion to active metabolite) Pneumocystis jirovecii pneumonia. It is often used to treat wounds, pyoderma, abscesses, bone and dental infections, and toxoplasmosis. Clindamycin is in a class of medications called lincomycin antibiotics. Should Sep 1, 2023 · contraindications ClindaMed oral solution is contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. rxweb. Inhibits bacterial protein synthesis by binding Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat. +44 (0)208 588 5411. * Almost any antibiotic can cause Clostridioides difficile. Clostridioides difficile–induced diarrhea and colitis*. Contraindications for Cleocin I. Customer Care direct line. Severe infections: 1,200-2,700 mg daily, may be increased up to 4,800 mg daily via IV in life-threatening situations. The volume of distribution has been variably estimated between 43-74 L. hypersensitivity to lincosamides. These include Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and other serious reactions. Nov 11, 2022 · The recommended dose is one applicatorful of clindamycin phosphate vaginal cream 2%, (5 grams containing approximately 100 mg of clindamycin phosphate) intravaginally, preferably at bedtime, for 3 CLEOCIN Vaginal Cream 2%, (clindamycin phosphate vaginal cream) is supplied as follows: 40 g tube (with 7 disposable applicators) NDC 0009-3448 Clindamycin-induced pseudomembranous enterocolitis (due to toxigenic C difficile) or lincosamide-induced disruption of GI flora is a serious adverse reaction in a number of species and can be lethal; thus, lincosamides are contraindicated for use in horses, guinea pigs, hamsters, rabbits, chinchillas, and ruminants. Each pre-filled, single-dose applicator delivers approximately 5 g of cream containing approximately 100 mg of clindamycin. Twenty studies, involving 1918 women, compared clindamycin plus an aminoglycoside (gentamicin for all studies except for one that used tobramycin) with another regimen. Rash, fever, and swollen lymph nodes. This drug is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. Clindamycin (brand names Antirobe®, Cleocin®, Clinsol®, Clintabs®) is an antibiotic used to treat a range of bacterial infections in dogs and cats. Oral solution: Manufacturer recommends 8–12 mg/kg daily for serious infections, 13–16 mg/kg daily for severe infections, or 17–25 mg/kg daily for more severe infections. Jun 26, 2023 · Metronidazole is one of the mainstay drugs for the treatment of anaerobic bacterial infections, protozoal infections, and microaerophilic bacterial infections. Topical clindamycin is used to help control acne. Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet. Clindamycin is an antibiotic which works by preventing bacterial growth and multiplication. 600 mg PO q8h x 7-10 days; Alt: 300-600mg IV q6h x 7-10 days First Dose: 300-600mg Jun 1, 2024 · Check with your doctor right away if you have blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you or your child are using this medicine. Contraindications Clindamycin is contraindicated in patients previously found to be sensitive to clindamycin or lincomycin or to any component of the formulation. StringCollection@459dda1a. Clindamycin works by preventing bacteria from producing proteins they need to grow and multiply. 70 mcg/mL at 6 hours. (See "Clostridioides difficile infection Indications and Dosage. (2) Avoid the eyes, mouth, paranasal creases, mucous membranes, and areas of broken, eczematous, or sunburned skin. Abstract. All doses are given in 2-4 equally divided doses. Anitbiotic. Bacterial Infection. 15% adapalene, and 3. 2% clindamycin phosphate, 0. Clindamycin - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version. For oral dosage forms (capsules and solution): For treatment of bacterial infections: Adults—150 to 300 milligrams (mg) every 6 hours. ep zt eo pg zf ou mb sa if wu